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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| RRRRRC | sulfide | Cholesterol |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00536 |
| Smiles | |
| Inchi Key | InChIKey=PTVOYPUWALSZBD-GNRRXMHWSA-N |
| Molecular weight | 1341.89 |
| Molecular formula | C63H115N21O9S |
| Chemical name | Peptide information |
| Sequence (one letter) | RRRRRC |
| Length | 6 |
| Peptide name | polyarginine |
| External ID | |
|---|---|
| CAS number | 1566560-83-5 |
| Other information | |
|---|---|
| Application | Synthesis |
| Additional function | Self-assembly, promising gene delivery carrier for intravenous therapy |
| Pharmacological class | other |
| Conjugate type | sulfide |
| Linker | N/A |
| Linker Type | sulfide |
| Small molecule | Cholesterol |
| Small molecule CAS | 57-88-5 |
| Small molecule structure | |
| Structure method | 1H- and 13C-NMR |
| NMR solvent | CDCl3 |
| Calculated properties | |
|---|---|
| LogP | -2.45154 |
| Rotatable bonds | 43 |
| H bond donor | 17 |
| H bond acceptor | 24 |
| Polar surface area (PSA) | 557.12000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Cholesterol-peptide hybrids to form liposome-like vesicles for gene delivery | 2013 | Tang, Qiong; Cao, Bin; Wu, Haiyan; Cheng, Gang | PLoS One | ||
