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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| HAIYPRH | PEG | Fallypride derivative |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00415 | Peptide information |
| Sequence (one letter) | HAIYPRH |
| Length | 7 |
| Peptide name | transferrin receptor binding peptide short (TfR-Ps) |
| External ID | |
|---|---|
| CAS number | 1609258-26-5 |
| Other information | |
|---|---|
| Application | Synthesis, peptidic carrier to facilitate blood-brain barrier transport |
| Additional function | Diagnosis, in vivo PET imaging or combined PET/optical imaging of hD2 receptors |
| Pharmacological class | other |
| Conjugate type | amide |
| Linker | N/A |
| Linker Type | PEG |
| Small molecule | Fallypride derivative |
| Small molecule CAS | 1609258-23-2 |
| Small molecule structure | |
| Structure method | DMSO-d6 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Shuttle-Cargo Fusion Molecules of Transport Peptides and the hD2/3 Receptor Antagonist Fallypride: A Feasible Approach To Preserve Ligand-Receptor Binding? | 2014 | Wangler, Carmen; Chowdhury, Shafinaz; Hofner, Georg; Djurova, Petia; Purisima, Enrico O.; Bartenstein, Peter; Wangler, Bjorn; Fricker, Gert; Wanner, Klaus T.; Schirrmacher, Ralf | Journal of Medicinal Chemistry | ||
