conjupepdb_log

View Conjugates details

ConjuPepDB ID: cpd00412

Chemical structure


molecule
3D viewer Help Icon Use the buttons at the bottom of Jsmol viewer to see different representations, ON/OFF Hydrogens, and ON/OFF rotation.

3D model is for representation purpose only.

cpd00412


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
RQIKIWFQNRRMKWKK PEG Fallypride derivative
Identification
ConjuPepDB ID

cpd00412

Peptide information
Sequence (one letter)

RQIKIWFQNRRMKWKK

Length

16

Peptide name

penetratin

External ID
CAS number

1609258-29-8

Other information
Application

Synthesis, peptidic carrier to facilitate blood-brain barrier transport

Additional function

Diagnosis, in vivo PET imaging or combined PET/optical imaging of hD2 receptors

Pharmacological class

other

Conjugate type

amide

Linker

N/A

Linker Type

PEG

Small molecule

Fallypride derivative

Small molecule CAS

1609258-23-2

Small molecule structure

Structure method

DMSO-d6

Citations
ID Title Year Authors Journal DOI

Cpdart0073

Shuttle-Cargo Fusion Molecules of Transport Peptides and the hD2/3 Receptor Antagonist Fallypride: A Feasible Approach To Preserve Ligand-Receptor Binding?

2014

Wangler, Carmen; Chowdhury, Shafinaz; Hofner, Georg; Djurova, Petia; Purisima, Enrico O.; Bartenstein, Peter; Wangler, Bjorn; Fricker, Gert; Wanner, Klaus T.; Schirrmacher, Ralf

Journal of Medicinal Chemistry

..