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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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| INXKYRLRY | triazole | 7-Amino-4-(azidomethyl)-2H-1-benzopyran-2-one |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00350 |
| Smiles | |
| Inchi Key | InChIKey=HDQPNLWDMVCMLH-ATXRJPNDSA-N |
| Molecular weight | 1490.79 |
| Molecular formula | C70H102N22O15 |
| Chemical name | Peptide information |
| Sequence (one letter) | INXKYRLRY |
| Length | 9 |
| Peptide name | nonapeptide |
| External ID | |
|---|---|
| CAS number | 1809332-12-4 |
| Other information | |
|---|---|
| Application | Synthesis, Y1-receptor binding |
| Additional function | Preparation of biotin and fluorophore-labelled peptides |
| Pharmacological class | other |
| Conjugate type | ether |
| Linker | N/A |
| Linker Type | triazole |
| Small molecule | 7-Amino-4-(azidomethyl)-2H-1-benzopyran-2-one |
| Small molecule CAS | 1186293-68-4 |
| Small molecule structure | |
| Calculated properties | |
|---|---|
| LogP | -5.07646 |
| Rotatable bonds | 43 |
| H bond donor | 18 |
| H bond acceptor | 25 |
| Polar surface area (PSA) | 623.75000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Propargyloxyproline regio- and stereoisomers for Click-conjugation of peptides: Synthesis and application in linear and cyclic peptides | 2015 | Northfield, Susan E.; Mountford, Simon J.; Wielens, Jerome; Liu, Mengjie; Zhang, Lei; Herzog, Herbert; Holliday, Nicholas D.; Scanlon, Martin J.; Parker, Michael W.; Chalmers, David K.; Thompson, Philip E. | Australian Journal of Chemistry | ||
