Use the buttons at the bottom of Jsmol viewer to see different representations, ON/OFF Hydrogens, and ON/OFF rotation.
3D model is for representation purpose only.
.
.
Schematic representation of peptide, linker and drug in the peptide-drug conjugates
 |
 |
 |
|
 |
|---|---|---|---|---|
| KKLFKKILKYL | 9-Fluorenylmethyl chloroformate |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00309 |
| Smiles | |
| Inchi Key | InChIKey=JJWOYBVOHUTSQU-UGEAPCRZSA-N |
| Molecular weight | 1668.03 |
| Molecular formula | C87H133N17[N-][N+]O14 |
| Chemical name | Peptide information |
| Sequence (one letter) | KKLFKKILKYL |
| Length | 11 |
| Peptide name | azidopeptides |
| External ID | |
|---|---|
| CAS number | 1803029-84-6 |
| Other information | |
|---|---|
| Application | Synthesis, solid-phase, conjugates derived from the antimicrobial cyclic decapeptide BPC199 |
| Additional function | Basis for the future development of libraries of homo- and heterodimeric antimicrobial peptides |
| Pharmacological class | other |
| Conjugate type | carbamate |
| Linker | yes |
| Small molecule | 9-Fluorenylmethyl chloroformate |
| Small molecule CAS | 28920-43-6 |
| Small molecule structure | |
| Structure method | 1H- 13C NMR |
| Calculated properties | |
|---|---|
| LogP | 3.69750 |
| Rotatable bonds | 58 |
| H bond donor | 17 |
| H bond acceptor | 19 |
| Polar surface area (PSA) | 534.11000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Solid-phase synthesis of peptide conjugates derived from the antimicrobial cyclic decapeptide BPC194 | 2015 | Vila, Silvia; Badosa, Esther; Montesinos, Emilio; Feliu, Lidia; Planas, Marta | European Journal of Organic Chemistry | ||
