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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| KKQKKFKKLQ | 9-Fluorenylmethyl chloroformate |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00303 |
| Smiles | |
| Inchi Key | InChIKey=GATYJXITXJSEIN-NZJLOJFYSA-N |
| Molecular weight | 1602.96 |
| Molecular formula | C82H126N18O15 |
| Chemical name | Peptide information |
| Sequence (one letter) | KKQKKFKKLQ |
| Length | 10 |
| Peptide name | alkynylptides |
| External ID | |
|---|---|
| CAS number | 1493847-05-4 |
| Other information | |
|---|---|
| Application | Synthesis, solid-phase, conjugates derived from the antimicrobial cyclic decapeptide BPC193 |
| Additional function | Basis for the future development of libraries of homo- and heterodimeric antimicrobial peptides |
| Pharmacological class | other |
| Conjugate type | carbamate |
| Linker | no |
| Small molecule | 9-Fluorenylmethyl chloroformate |
| Small molecule CAS | 28920-43-6 |
| Small molecule structure | |
| Structure method | 1H- 13C NMR |
| Calculated properties | |
|---|---|
| LogP | -0.65561 |
| Rotatable bonds | 61 |
| H bond donor | 18 |
| H bond acceptor | 19 |
| Polar surface area (PSA) | 554.84000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Solid-phase synthesis of peptide conjugates derived from the antimicrobial cyclic decapeptide BPC194 | 2015 | Vila, Silvia; Badosa, Esther; Montesinos, Emilio; Feliu, Lidia; Planas, Marta | European Journal of Organic Chemistry | ||
