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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| GYVS+FS | bisarylethyne |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00263 |
| Smiles | |
| Inchi Key | InChIKey=CPNWRIQVGVFJLX-GKCWTWCASA-N |
| Molecular weight | 714.301 |
| Molecular formula | C37H42N6O9 |
| Chemical name | Peptide information |
| Sequence (one letter) | GYVS+FS |
| Length | 7 |
| Peptide name | tetrapeptide+dipeptide |
| External ID | |
|---|---|
| CAS number | 1672675-13-6 |
| Other information | |
|---|---|
| Application | Synthesis, potentially interesting redox- and photochemical properties |
| Additional function | possible applications in medicinal chemistry and advanced materials |
| Pharmacological class | other |
| Conjugate type | amide |
| Linker | no |
| Small molecule | bisarylethyne |
| Small molecule CAS | 1672675-08-9 |
| Small molecule structure | |
| Calculated properties | |
|---|---|
| LogP | -1.73483 |
| Rotatable bonds | 18 |
| H bond donor | 9 |
| H bond acceptor | 10 |
| Polar surface area (PSA) | 263.27000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Synthesis of bisarylethyne-peptide conjugates | 2015 | Strack, Martin; Langklotz, Sina; Bandow, Julia E.; Metzler-Nolte, Nils; Bauke Albada, H. | Organic Chemistry Frontiers | ||
