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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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| AELDRWEKIRLRPAACXXXXXXXXXXX | PEG | pyrrole-imidazole polyamide |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00258 |
| Smiles | |
| Inchi Key | InChIKey=KJZOETFEHLJCIU-MCYAIIKONA-N |
| Molecular weight | 3347.71 |
| Molecular formula | C151H226N50O36S |
| Chemical name | Peptide information |
| Sequence (one letter) | AELDRWEKIRLRPAACXXXXXXXXXXX |
| Length | 27 |
| Peptide name | functionalized peptide epitope |
| External ID | |
|---|---|
| CAS number | 1885110-04-2 |
| Other information | |
|---|---|
| Application | Synthesis, functionalize DNA nanostructures (not successfull) |
| Additional function | Possible biomedical and bionanotechnological applications |
| Pharmacological class | other |
| Conjugate type | amide |
| Linker | N/A |
| Linker Type | PEG |
| Small molecule | pyrrole-imidazole polyamide |
| Small molecule CAS | 1885109-92-1 |
| Small molecule structure | |
| Calculated properties | |
|---|---|
| LogP | -13.34885 |
| Rotatable bonds | 102 |
| H bond donor | 39 |
| H bond acceptor | 50 |
| Polar surface area (PSA) | 1245.99000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Efficient synthesis of peptide and protein functionalized pyrrole-imidazole polyamides using native chemical ligation | 2015 | Janssen, Brian M. G.; van Ommeren, Sven P. F. I.; Merkx, Maarten | International Journal of Molecular Sciences | ||
