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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| XRNLF | biotin |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00248 |
| Smiles | |
| Inchi Key | InChIKey=ROEHMAQSUAZPHR-LKDKIUHVSA-N |
| Molecular weight | 1132.64 |
| Molecular formula | C63H88N8O9S |
| Chemical name | Peptide information |
| Sequence (one letter) | XRNLF |
| Length | 5 |
| Peptide name | pentapeptide |
| External ID | |
|---|---|
| CAS number | 1781222-45-4 |
| Other information | |
|---|---|
| Application | Synthesis, incorporation of complex N-substituents at both termini and at internal positions |
| Additional function | Modifications of biologically relevant peptides: fluorescent labeling, PEGylation, glycosylation, etc. |
| Pharmacological class | other |
| Conjugate type | sulfonamide |
| Linker | no |
| Small molecule | biotin |
| Small molecule CAS | 58-85-5 |
| Small molecule structure | |
| Calculated properties | |
|---|---|
| LogP | 10.77108 |
| Rotatable bonds | 31 |
| H bond donor | 6 |
| H bond acceptor | 10 |
| Polar surface area (PSA) | 253.71000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Aminocatalysis-Mediated on-Resin Ugi Reactions: Application in the Solid-Phase Synthesis of N-Substituted and Tetrazolo Lipopeptides and Peptidosteroids | 2015 | Morales, Fidel E.; Garay, Hilda E.; Munoz, Daniela F.; Augusto, Yarelys E.; Otero-Gonzalez, Anselmo J.; Reyes Acosta, Osvaldo; Rivera, Daniel G. | Organic Letters | ||
