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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| VXGSWSXXFQVIA | PEG | Rifampicin |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00236 | Peptide information |
| Sequence (one letter) | VXGSWSXXFQVIA |
| Length | 13 |
| Peptide name | tridecaptin A1 |
| External ID | |
|---|---|
| CAS number | 1832593-77-7 |
| Other information | |
|---|---|
| Application | Antimicrobial, antibacterial, Gram-negative Klebsiella) |
| Additional function | Increased efficacy |
| Pharmacological class | antimicrobial, antibacterial |
| Conjugate type | amide |
| Linker | N/A |
| Linker Type | PEG |
| Small molecule | Rifampicin |
| Small molecule CAS | 13292-46-1 |
| Small molecule structure | |
| Structure method | 1H- anf 13C-NMR |
| NMR solvent | CDCl3 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Synthesis of Tridecaptin-Antibiotic Conjugates with in Vivo Activity against Gram-Negative Bacteria | 2015 | Cochrane, Stephen A.; Li, Xuefeng; He, Sisi; Yu, Min; Wu, Min; Vederas, John C. | Journal of Medicinal Chemistry | ||
