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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| XAFKK | 4-Pentynoic acid |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00153 |
| Smiles | |
| Inchi Key | InChIKey=NWLJCYXAACBVCO-GKKOWRRISA-N |
| Molecular weight | 640.37 |
| Molecular formula | C32H48N8O6 |
| Chemical name | Peptide information |
| Sequence (one letter) | XAFKK |
| Length | 5 |
| Peptide name | autoinducing peptide (AIP) |
| External ID | |
|---|---|
| CAS number | 2093165-89-8 |
| Other information | |
|---|---|
| Application | Antimicrobial therapy, antibacterial (Staphylococcus aureus) |
| Additional function | Fluorophore and cytotoxic photosensitizer conjugations |
| Pharmacological class | antimicrobial, antibacterial |
| Conjugate type | amide |
| Linker | no |
| Small molecule | 4-Pentynoic acid |
| Small molecule CAS | 6089-09-04 |
| Calculated properties | |
|---|---|
| LogP | -2.56012 |
| Rotatable bonds | 13 |
| H bond donor | 8 |
| H bond acceptor | 8 |
| Polar surface area (PSA) | 226.64000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Truncated Autoinducing Peptide Conjugates Selectively Recognize and Kill Staphylococcus aureus | 2017 | Tsuchikama, Kyoji; Shimamoto, Yasuhiro; Anami, Yasuaki | ACS Infectious Diseases | ||
