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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| XRRR | Nalidixic acid |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00135 |
| Smiles | |
| Inchi Key | InChIKey=UZJJPVGJSHLUNM-NJDAHSKKSA-N |
| Molecular weight | 699.404 |
| Molecular formula | C30H49N15O5 |
| Chemical name | Peptide information |
| Sequence (one letter) | XRRR |
| Length | 4 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 2133449-63-3 |
| Other information | |
|---|---|
| Application | Antimicrobial drug delivery |
| Additional function | Improve activity and fluorescent labeling |
| Pharmacological class | antimicrobial, antibacterial |
| Conjugate type | amide |
| Linker | no |
| Small molecule | Nalidixic acid |
| Small molecule CAS | 0389-08-02 |
| Calculated properties | |
|---|---|
| LogP | -4.55301 |
| Rotatable bonds | 20 |
| H bond donor | 10 |
| H bond acceptor | 16 |
| Polar surface area (PSA) | 356.79000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Enhancing the Potency of Nalidixic Acid toward a Bacterial DNA Gyrase with Conjugated Peptides | 2017 | Ahmed, Marya; Kelley, Shana O. | ACS Chemical Biology | ||
