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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| XRXRXRX | Nalidixic acid |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00133 |
| Smiles | |
| Inchi Key | InChIKey=KKKMXBILUUIZPF-UQTYJRDZSA-N |
| Molecular weight | 1311.87 |
| Molecular formula | C66H109N19O9 |
| Chemical name | Peptide information |
| Sequence (one letter) | XRXRXRX |
| Length | 7 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 2133449-66-6 |
| Other information | |
|---|---|
| Application | Antimicrobial drug delivery |
| Additional function | Improve activity and fluorescent labeling |
| Pharmacological class | antimicrobial, antibacterial |
| Conjugate type | amide |
| Linker | no |
| Small molecule | Nalidixic acid |
| Small molecule CAS | 0389-08-02 |
| Calculated properties | |
|---|---|
| LogP | 1.70789 |
| Rotatable bonds | 36 |
| H bond donor | 14 |
| H bond acceptor | 20 |
| Polar surface area (PSA) | 473.19000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Enhancing the Potency of Nalidixic Acid toward a Bacterial DNA Gyrase with Conjugated Peptides | 2017 | Ahmed, Marya; Kelley, Shana O. | ACS Chemical Biology | ||
