conjupepdb_log

View Conjugates details

ConjuPepDB ID: cpd00094

Chemical structure


molecule
3D viewer Help Icon Use the buttons at the bottom of Jsmol viewer to see different representations, ON/OFF Hydrogens, and ON/OFF rotation.

3D model is for representation purpose only.

cpd00094


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
GTGVP butyric acid 3,4-Dihydro-4-oxo-2-quinazolinebutanoic acid
Identification
ConjuPepDB ID

cpd00094

Smiles
Inchi Key

InChIKey=ZYTBCIZTNUBFRZ-CVTNIXEKSA-N

Molecular weight

629.281

Molecular formula

C29H39N7O9

Chemical name
Peptide information
Sequence (one letter)

GTGVP

Length

5

Peptide name

N/A

External ID
CAS number

2411424-15-0

Other information
Application

Antimicrobial therapy, antibacteraial (Gramm-positive and negative)

Additional function

Improve effect

Pharmacological class

antimicrobial, antibacterial

Conjugate type

amide

Linker

N/A

Linker Type

butyric acid

Small molecule

3,4-Dihydro-4-oxo-2-quinazolinebutanoic acid

Small molecule CAS

95494-51-2

Small molecule structure

Structure method

1H- and 13C-NMR

Calculated properties
LogP

-2.17438

Rotatable bonds

14

H bond donor

7

H bond acceptor

11

Polar surface area (PSA)

235.70000

Citations
ID Title Year Authors Journal DOI

Cpdart0032

Effect of low charge and high hydrophobicity on antimicrobial activity of the quinazolinone-peptide conjugates

2018

Rakesh, Kadallipura Puttaswamy; Ramesh, Suhas; Shivakumar; Gowda, Dase Channe

Russian Journal of Bioorganic Chemistry

..