Use the buttons at the bottom of Jsmol viewer to see different representations, ON/OFF Hydrogens, and ON/OFF rotation.
3D model is for representation purpose only.
.
.
Schematic representation of peptide, linker and drug in the peptide-drug conjugates
 |
 |
 |
|
 |
|---|---|---|---|---|
| PWF | (R)-5-oxo-2-pyrrolidinecarboxamide |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00084 | Peptide information |
| Sequence (one letter) | PWF |
| Length | 3 |
| Peptide name | tripeptide, linear |
| External ID | |
|---|---|
| CAS number | 2230864-63-6 |
| Other information | |
|---|---|
| Application | Synthesis, tryptophan chemoselective beta?position conjugation |
| Additional function | Possible appications as protein labeling and various bioconjugations |
| Pharmacological class | other |
| Conjugate type | amide |
| Linker | no |
| Small molecule | (R)-5-oxo-2-pyrrolidinecarboxamide |
| Small molecule CAS | 118929-65-0 |
| Small molecule structure | |
| Structure method | NMR |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Chemoselective Peptide Modification via Photocatalytic Tryptophan β-Position Conjugation | 2018 | Yu, Younong; Zhang, Li-Kang; Buevich, Alexei V.; Li, Guoqing; Tang, Haiqun; Vachal, Petr; Colletti, Steven L.; Shi, Zhi-Cai | Journal of the American Chemical Society | ||
