3D model is for representation purpose only.
.
.
LFMSCRTWKHYEQ | triazole | Fluorescein |
Identification | |
---|---|
ConjuPepDB ID | cpd00064 |
Smiles | |
Inchi Key | InChIKey=BFSKLYJKRIXQMX-FTZLZTNYSA-N |
Molecular weight | 2453.95 |
Molecular formula | C113H143N27O28S4 |
Chemical name | Peptide information |
Sequence (one letter) | LFMSCRTWKHYEQ |
Length | 13 |
Peptide name | model peptide |
External ID | |
---|---|
CAS number | 2247055-87-2 |
Other information | |
---|---|
Application | Synthesis, cysteine-Selective conjugation to prepare antibody-drog conjugates |
Additional function | Posible applications as various imaging and therapeutic conjugates |
Pharmacological class | anticancer |
Conjugate type | sulfide |
Linker | N/A |
Linker Type | triazole |
Small molecule | Fluorescein |
Small molecule CAS | 2321-07-05 |
Calculated properties | |
---|---|
LogP | -5.63040 |
Rotatable bonds | 67 |
H bond donor | 28 |
H bond acceptor | 34 |
Polar surface area (PSA) | 865.86000 |
Citations | |||||
---|---|---|---|---|---|
ID | Title | Year | Authors | Journal | DOI |
N-Methyl-N-phenylvinylsulfonamides for Cysteine-Selective Conjugation | 2018 | Huang, Rong; Li, Zhihong; Sheng, Yao; Yu, Jianghui; Wu, Yue; Zhan, Yuexiong; Chen, Hongli; Jiang, Biao | Organic Letters |