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View Conjugates details

ConjuPepDB ID: cpd00058

Chemical structure


molecule
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cpd00058


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
XVVX PEG N-(4-Hydroxyphenyl)-N-methylethenesulfonamide
Identification
ConjuPepDB ID

cpd00058

Smiles
Inchi Key

InChIKey=YEMAINFEWHAGFT-PEWLHXCKSA-N

Molecular weight

1121.66

Molecular formula

C58H91N9O11S

Chemical name
Peptide information
Sequence (one letter)

XVVX

Length

4

Peptide name

tripeptide

External ID
CAS number

2265215-71-0

Other information
Application

Synthesis, cysteine-Selective conjugation to prepare antibody-drog conjugates

Additional function

Posible applications as various imaging and therapeutic conjugates

Pharmacological class

anticancer

Conjugate type

amide

Linker

N/A

Linker Type

PEG

Small molecule

N-(4-Hydroxyphenyl)-N-methylethenesulfonamide

Small molecule CAS

2135640-37-6

Small molecule structure

Calculated properties
LogP

5.68169

Rotatable bonds

32

H bond donor

3

H bond acceptor

13

Polar surface area (PSA)

235.14000

Citations
ID Title Year Authors Journal DOI

Cpdart0030

N-Methyl-N-phenylvinylsulfonamides for Cysteine-Selective Conjugation

2018

Huang, Rong; Li, Zhihong; Sheng, Yao; Yu, Jianghui; Wu, Yue; Zhan, Yuexiong; Chen, Hongli; Jiang, Biao

Organic Letters

..