Use the buttons at the bottom of Jsmol viewer to see different representations, ON/OFF Hydrogens, and ON/OFF rotation.
3D model is for representation purpose only.
.
.
Schematic representation of peptide, linker and drug in the peptide-drug conjugates
 |
 |
 |
|
 |
|---|---|---|---|---|
| DSLKSYWYLQ KFSWR | 4-(2-Benzothiazolylamino)-4-oxobutanoic acid (BenzoTZ-C2) |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00013 | Peptide information |
| Sequence (one letter) | DSLKSYWYLQ KFSWR |
| Length | 16 |
| Peptide name | CPP2 |
| External ID | |
|---|---|
| CAS number | 2415537-31-2 |
| Other information | |
|---|---|
| Application | Anticancer therapy, breast cancer (MCF-7 cell line) |
| Additional function | Improve activity and decrease toxicity |
| Pharmacological class | anticancer |
| Linker | N/A |
| Small molecule | 4-(2-Benzothiazolylamino)-4-oxobutanoic acid (BenzoTZ-C2) |
| Small molecule CAS | 79888-43-0 |
| Small molecule structure | |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Increasing the potential of cell-penetrating peptides for cancer therapy using a new pentagonal scaffold. | 2019 | Duarte, Diana; Fraga, Alexandra G.; Pedrosa, Jorge; Martel, Fátima; Vale, Nuno | European Journal of Pharmacology | ||
