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Microwave-assisted formation of peptide-vitamin conjugates

Authors: El-Nachef, Claudia; Bajaj, Kiran; Koblick, Jacqueline; Katritzky, Alan R.; European Journal of Organic Chemistry; (2012); 10.1002/ejoc.201200323

Amino acid and peptide conjugates with vitamin B3, H, E and D3 were synthesized by using microwave irradiation in good to satisfactory yields. In addition, a novel benzotriazole‐activated biotin intermediate has been introduced, which could serve as an alternative biotinylation agent.

Cpdart0106

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