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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| XASXQSL | Doxorubicin |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01494 |
| Smiles | |
| Molecular weight | 1367.57 |
| Molecular formula | C63H85N9O25 |
| Chemical name | Peptide information |
| Sequence (one letter) | XASXQSL |
| Length | 7 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 440357-47-1 |
| Other information | |
|---|---|
| Application | Synthesis |
| Additional function | Anyalitics |
| Pharmacological class | anticancer |
| Conjugate type | amide |
| Linker | no |
| Small molecule | Doxorubicin |
| Small molecule CAS | 23214-92-8 |
| Structure method | HPLC, FT-IR |
| Calculated properties | |
|---|---|
| LogP | -3.23749 |
| Rotatable bonds | 29 |
| H bond donor | 17 |
| H bond acceptor | 25 |
| Polar surface area (PSA) | 545.14000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Employment of on-line FT-IR spectroscopy to monitor the deprotection of a 9-fluorenylmethyl protected carboxylic acid peptide conjugate of doxorubicin | 2002 | Cameron, Mark; Zhou, George X.; Hicks, Micheal B.; Antonucci, Vincent; Ge, Zhihong; Lieberman, David R.; Lynch, Joesph E.; Shi, Yao-Jun | Journal of Pharmaceutical and Biomedical Analysis | ||
