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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| XRKKV | ß-alanine | 3,6-Diamino-9(10H)-acridinone |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01493 |
| Smiles | |
| Molecular weight | 1533.93 |
| Molecular formula | C71H119N23O15 |
| Chemical name | Peptide information |
| Sequence (one letter) | XRKKV |
| Length | 5 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 449200-57-1 |
| Other information | |
|---|---|
| Application | Synthesis |
| Additional function | DNA binding |
| Pharmacological class | other |
| Conjugate type | amide |
| Linker | N/A |
| Linker Type | ß-alanine |
| Small molecule | 3,6-Diamino-9(10H)-acridinone |
| Small molecule CAS | 42832-87-1 |
| Structure method | HPLC, LC-MS |
| Calculated properties | |
|---|---|
| LogP | -6.60728 |
| Rotatable bonds | 54 |
| H bond donor | 23 |
| H bond acceptor | 28 |
| Polar surface area (PSA) | 629.06000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Solid-Phase Synthesis of Symmetrical 3,6-Bispeptide-Acridone Conjugates | 2002 | Ladame, Sylvain; Harrison, R. John; Neidle, Stephen; Balasubramanian, Shankar | Organic Letters | ||
