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View Conjugates details

ConjuPepDB ID: cpd01196

Chemical structure


molecule
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cpd01196


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
NFPI AZT monophosphate
Identification
ConjuPepDB ID

cpd01196

Smiles
Molecular weight

1108.42

Molecular formula

C57H61N10O12P

Chemical name
Peptide information
Sequence (one letter)

NFPI

Length

4

Peptide name

tetrapeptide

External ID
CAS number

1029947-71-4

Other information
Application

Antibiotic, antiviral (HIV)

Additional function

Targeting HIV-infected cells

Pharmacological class

antimicrobial, antiviral

Conjugate type

fosfamide

Linker

no

Small molecule

AZT monophosphate

Small molecule CAS

29706-85-2

Structure method

1H-NMR, HPLC, ESI-MS

NMR solvent

CDCl3

Calculated properties
LogP

6.02343

Rotatable bonds

24

H bond donor

5

H bond acceptor

11

Polar surface area (PSA)

277.49000

Citations
ID Title Year Authors Journal DOI

cpdart0185

AZT and AZT-monophosphate prodrugs incorporating HIV-protease substrate fragment: synthesis and evaluation as specific drug delivery systems

2006

Liotard, Jean-Francois; Mehiri, Mohamed; Di Giorgio, Audrey; Boggetto, Nicole; Reboud-Ravaux, Michele; Aubertin, Anne-Marie; Condom, Roger; Patino, Nadia

Antiviral Chemistry & Chemotherapy

..