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ConjuPepDB ID: cpd01195

Chemical structure


molecule
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cpd01195


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
ANFPI AZT monophosphate
Identification
ConjuPepDB ID

cpd01195

Smiles
Molecular weight

1221.5

Molecular formula

C63H72N11O13P

Chemical name
Peptide information
Sequence (one letter)

ANFPI

Length

5

Peptide name

N/A

External ID
CAS number

1029947-72-5

Other information
Application

Antibiotic, antiviral (HIV)

Additional function

Targeting HIV-infected cells

Pharmacological class

antimicrobial, antiviral

Conjugate type

fosfamide

Linker

no

Small molecule

AZT monophosphate

Small molecule CAS

29706-85-2

Structure method

1H-NMR, HPLC, ESI-MS

NMR solvent

CDCl3

Calculated properties
LogP

6.75213

Rotatable bonds

28

H bond donor

6

H bond acceptor

12

Polar surface area (PSA)

306.59000

Citations
ID Title Year Authors Journal DOI

cpdart0185

AZT and AZT-monophosphate prodrugs incorporating HIV-protease substrate fragment: synthesis and evaluation as specific drug delivery systems

2006

Liotard, Jean-Francois; Mehiri, Mohamed; Di Giorgio, Audrey; Boggetto, Nicole; Reboud-Ravaux, Michele; Aubertin, Anne-Marie; Condom, Roger; Patino, Nadia

Antiviral Chemistry & Chemotherapy

..