3D model is for representation purpose only.
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RWRWRWRW | glutaric acid | doxorubicin |
Identification | |
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ConjuPepDB ID | cpd00002 |
Smiles | |
Inchi Key | InChIKey=BAAHWYPUCXORMD-VREYHHINSA-N |
Molecular weight | 2024.94 |
Molecular formula | C100H124N26O21 |
Chemical name | Peptide information |
Sequence (one letter) | RWRWRWRW |
Length | 8 |
Peptide name | N/A |
External ID | |
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CAS number | 1417821-47-6 |
Other information | |
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Application | Anticancer therapy (prodrug) |
Additional function | Targeting |
Pharmacological class | anticancer |
Conjugate type | amide |
Linker | N/A |
Linker Type | glutaric acid |
Small molecule | doxorubicin |
Small molecule CAS | 23214-92-8 |
Small molecule structure | |
Structure method | NMR |
NMR solvent | DMSO-d6 |
Calculated properties | |
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LogP | -0.64034 |
Rotatable bonds | 51 |
H bond donor | 26 |
H bond acceptor | 33 |
Polar surface area (PSA) | 808.79000 |
Citations | |||||
---|---|---|---|---|---|
ID | Title | Year | Authors | Journal | DOI |
Design and biological evaluation of cell-penetrating peptide-doxorubicin conjugates as prodrugs. | 2013 | Nasrolahi Shirazi, Amir; Tiwari, Rakesh; Chhikara, Bhupender S; Mandal, Dindyal; Parang, Keykavous | Molecular pharmaceutics |