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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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| DGEXG | 25,26,27,28-tetrabutoxy-pentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3,5,7(28),9,11,13(27),15,17,19(26),21,23-dodecaene-5,11,17,23-tetracarboxylic acid |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01586 |
| Smiles | |
| Molecular weight | 2720.98 |
| Molecular formula | C128H144N24O44 |
| Chemical name | Peptide information |
| Sequence (one letter) | DGEXG |
| Length | 5 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 202348-49-0 |
| Other information | |
|---|---|
| Application | Synthesis |
| Additional function | Antibody mimicking |
| Pharmacological class | other |
| Conjugate type | amide |
| Linker | no |
| Small molecule | 25,26,27,28-tetrabutoxy-pentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3,5,7(28),9,11,13(27),15,17,19(26),21,23-dodecaene-5,11,17,23-tetracarboxylic acid |
| Small molecule CAS | 202348-47-8 |
| Structure method | 1H NMR |
| NMR solvent | DMSO-d6 |
| Calculated properties | |
|---|---|
| LogP | -5.56711 |
| Rotatable bonds | 40 |
| H bond donor | 32 |
| H bond acceptor | 44 |
| Polar surface area (PSA) | 1033.72000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
A calixarene with four peptide loops: an antibody mimic for recognition of protein surfaces | 1997 | Hamuro, Yoshitomo; Calama, Mercedes Crego; Park, Hyung Soon; Hamilton, Andrew D. | Angewandte Chemie, International Edition in English | ||
