Use the buttons at the bottom of Jsmol viewer to see different representations, ON/OFF Hydrogens, and ON/OFF rotation.
3D model is for representation purpose only.
.
.
Schematic representation of peptide, linker and drug in the peptide-drug conjugates
 |
 |
 |
|
 |
|---|---|---|---|---|
| GGFG | propyl | Camptothecin |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01543 |
| Smiles | |
| Molecular weight | 839.349 |
| Molecular formula | C43H49N7O11 |
| Chemical name | Peptide information |
| Sequence (one letter) | GGFG |
| Length | 4 |
| Peptide name | tetrapeptide |
| External ID | |
|---|---|
| CAS number | 192991-32-5 |
| Other information | |
|---|---|
| Application | Synthesis |
| Pharmacological class | anticancer |
| Conjugate type | amide |
| Linker | N/A |
| Linker Type | propyl |
| Small molecule | Camptothecin |
| Small molecule CAS | 7689-03-04 |
| Calculated properties | |
|---|---|
| LogP | -0.37840 |
| Rotatable bonds | 18 |
| H bond donor | 6 |
| H bond acceptor | 10 |
| Polar surface area (PSA) | 243.69000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Determinants for the drug release from T-0128, camptothecin analog-carboxymethyl dextran conjugate | 2000 | Harada, M.; Sakakibara, H.; Yano, T.; Suzuki, T.; Okuno, S. | Journal of Controlled Release | ||
