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ConjuPepDB ID: cpd01532

Chemical structure


molecule
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cpd01532


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
AKSRA succinic acid Anthraquinone derivative
Identification
ConjuPepDB ID

cpd01532

Smiles
Molecular weight

879.424

Molecular formula

C41H57N11O11

Chemical name
Peptide information
Sequence (one letter)

AKSRA

Length

5

Peptide name

partially truncated AP-1-like peptide

External ID
CAS number

332180-28-6

Other information
Application

Anticancer therapy, cell proliferation and malignant transformation inhibition

Additional function

AP-1 transcription factor inhibition

Pharmacological class

anticancer

Conjugate type

amide

Linker

N/A

Linker Type

succinic acid

Small molecule

Anthraquinone derivative

Small molecule CAS

69940-76-7

Structure method

EMSA

Calculated properties
LogP

-4.70735

Rotatable bonds

26

H bond donor

13

H bond acceptor

16

Polar surface area (PSA)

366.22000

Citations
ID Title Year Authors Journal DOI

cpdart0237

Anthraquinone-peptides as inhibitors of AP-1 transcription factor

2001

Ijaz, T.; Tran, P.; Ruparelia, K. C.; Teesdale-Spittle, P. H.; Orr, S.; Patterson, L. H.

Bioorganic & Medicinal Chemistry Letters

..