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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| XHWSYKLRPG | Protoporphyrin IX |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01422 |
| Smiles | |
| Molecular weight | 1796.89 |
| Molecular formula | C93H116N22O16 |
| Chemical name | Peptide information |
| Sequence (one letter) | XHWSYKLRPG |
| Length | 10 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 609767-63-7 |
| Other information | |
|---|---|
| Application | Anticancer therapy, photosensitizer |
| Additional function | Targeting gonadotropin-releasing hormone (GnH) receptors |
| Pharmacological class | anticancer |
| Conjugate type | amide |
| Linker | no |
| Small molecule | Protoporphyrin IX |
| Small molecule CAS | 0553-12-8 |
| Structure method | 1H NMR, RP-HPLC |
| NMR solvent | DMSO-d6-H2O |
| Calculated properties | |
|---|---|
| LogP | 1.37060 |
| Rotatable bonds | 44 |
| H bond donor | 21 |
| H bond acceptor | 22 |
| Polar surface area (PSA) | 595.89000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Receptor-Mediated Targeting of a Photosensitizer by Its Conjugation to Gonadotropin-Releasing Hormone Analogues | 2003 | Rahimipour, Shai; Ben-Aroya, Nurit; Ziv, Keren; Chen, Alon; Fridkin, Mati; Koch, Yitzhak | Journal of Medicinal Chemistry | ||
