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View Conjugates details

ConjuPepDB ID: cpd01397

Chemical structure


molecule
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cpd01397


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
XRGD butyric acid Porfirin derivative
Identification
ConjuPepDB ID

cpd01397

Smiles
Molecular weight

2248.77

Molecular formula

C110H120N12O40

Chemical name
Peptide information
Sequence (one letter)

XRGD

Length

4

Peptide name

tetrapeptide

External ID
CAS number

737765-75-2

Other information
Application

Anticancer therapy, photosensitizer

Pharmacological class

anticancer

Conjugate type

amide

Linker

N/A

Linker Type

butyric acid

Small molecule

Porfirin derivative

Small molecule CAS

219322-73-3

Structure method

1H- and 13C NMR, MS-MALDI

NMR solvent

DMSO-d6

Calculated properties
LogP

0.69824

Rotatable bonds

49

H bond donor

12

H bond acceptor

33

Polar surface area (PSA)

719.57000

Citations
ID Title Year Authors Journal DOI

cpdart0214

Efficient synthesis of RGD-containing cyclic peptide-porphyrin conjugates by ring-closing metathesis on solid support

2004

Chaleix, Vincent; Sol, Vincent; Guilloton, Michel; Granet, Robert; Krausz, Pierre

Tetrahedron Letters

..