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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| EDG | Prednisolone |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01376 |
| Smiles | |
| Inchi Key | InChIKey=HPRGOBVWFWGENY-UHFFFAOYSA-N |
| Molecular weight | 761.301 |
| Molecular formula | C36H47N3O15 |
| Chemical name | Peptide information |
| Sequence (one letter) | EDG |
| Length | 3 |
| Peptide name | tripeptide |
| External ID | |
|---|---|
| CAS number | 757954-21-5 |
| Other information | |
|---|---|
| Application | Immunosuppressive therapy |
| Pharmacological class | Anti-inflammatory |
| Conjugate type | hydrazide |
| Linker | no |
| Small molecule | Prednisolone |
| Small molecule CAS | 50-24-8 |
| Structure method | 1H NMR, HPLC |
| NMR solvent | DMSO-d11 |
| Calculated properties | |
|---|---|
| LogP | -1.63431 |
| Rotatable bonds | 18 |
| H bond donor | 8 |
| H bond acceptor | 14 |
| Polar surface area (PSA) | 300.10000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
The synthesis and immunosuppressive activities of steroid-urotoxin linkers | 2004 | Wang, Chao; Zhao, Ming; Qiu, Xuecai; Peng, Shiqi | Bioorganic & Medicinal Chemistry | ||
