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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| KK | Porphyrin derivative |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01314 |
| Smiles | |
| Molecular weight | 1284.64 |
| Molecular formula | C69H80N20O4S |
| Chemical name | Peptide information |
| Sequence (one letter) | KK |
| Length | 2 |
| Peptide name | dipeptide |
| External ID | |
|---|---|
| CAS number | 863708-68-3 |
| Other information | |
|---|---|
| Application | Anticancer therapy, photosensitizer |
| Additional function | Improving water solubility |
| Pharmacological class | anticancer |
| Conjugate type | tiocarbamoyl |
| Linker | no |
| Small molecule | Porphyrin derivative |
| Small molecule CAS | 67605-64-5 |
| Structure method | 1H and 13C NMR, HPLC |
| NMR solvent | CDCl3 |
| Calculated properties | |
|---|---|
| LogP | 6.00632 |
| Rotatable bonds | 29 |
| H bond donor | 18 |
| H bond acceptor | 16 |
| Polar surface area (PSA) | 423.53000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Synthesis and characterization of positively charged porphyrin-peptide conjugates | 2005 | Sibrian-Vazquez, Martha; Jensen, Timothy J.; Fronczek, Frank R.; Hammer, Robert P.; Vicente, M. Graca H. | Bioconjugate Chemistry | ||
