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View Conjugates details

ConjuPepDB ID: cpd01299

Chemical structure


molecule
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cpd01299


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
GRKKRRQRRRPPQ PEG Porphine derivative
Identification
ConjuPepDB ID

cpd01299

Smiles
Molecular weight

3075.56

Molecular formula

C142H206N42O36

Chemical name
Peptide information
Sequence (one letter)

GRKKRRQRRRPPQ

Length

13

Peptide name

N/A

External ID
CAS number

880760-18-9

Other information
Application

Anticancer therapy, photosensitizer

Additional function

Improving solubility an cell penetration

Pharmacological class

anticancer

Conjugate type

amide

Linker

N/A

Linker Type

PEG

Small molecule

Porphine derivative

Small molecule CAS

880760-16-7

Structure method

1H NMR, HPLC

NMR solvent

D2O

Calculated properties
LogP

-13.77138

Rotatable bonds

106

H bond donor

41

H bond acceptor

58

Polar surface area (PSA)

1251.65000

Citations
ID Title Year Authors Journal DOI

cpdart0199

Peptide-Mediated Cell Transport of Water Soluble Porphyrin Conjugates

2006

Sibrian-Vazquez, Martha; Jensen, Timothy J.; Hammer, Robert P.; Vicente, M. Graca H.

Journal of Medicinal Chemistry

..