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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| GSI | 9-Aminoacridine |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01223 |
| Smiles | |
| Inchi Key | InChIKey=PCYIKEOOYJMOEQ-UHFFFAOYSA-N |
| Molecular weight | 546.295 |
| Molecular formula | C30H38N6O4 |
| Chemical name | Peptide information |
| Sequence (one letter) | GSI |
| Length | 3 |
| Peptide name | tripeptide |
| External ID | |
|---|---|
| CAS number | 920746-46-9 |
| Other information | |
|---|---|
| Application | Investigation of acridine–peptide conjugates |
| Additional function | prion binding affinity |
| Pharmacological class | other |
| Conjugate type | amide |
| Linker | no |
| Small molecule | 9-Aminoacridine |
| Small molecule CAS | 90-45-9 |
| Structure method | 1H NMR, HPLC |
| NMR solvent | DMSO-d6 |
| Calculated properties | |
|---|---|
| LogP | 2.31886 |
| Rotatable bonds | 13 |
| H bond donor | 4 |
| H bond acceptor | 7 |
| Polar surface area (PSA) | 145.24000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Acridin-9-yl exchange: a proposal for the action of some 9-aminoacridine drugs | 2006 | Sebestik, Jaroslav; Safarik, Martin; Stibor, Ivan; Hlavacek, Jan | Biopolymers | ||
