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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| LTVSPWY | Vitamin E succinate |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01183 |
| Smiles | |
| Molecular weight | 1376.82 |
| Molecular formula | C76H112N8O15 |
| Chemical name | Peptide information |
| Sequence (one letter) | LTVSPWY |
| Length | 7 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 941292-78-0 |
| Other information | |
|---|---|
| Application | Anticancer therapy, breast tumorts |
| Additional function | Targering |
| Pharmacological class | anticancer |
| Conjugate type | amide |
| Linker | no |
| Small molecule | Vitamin E succinate |
| Small molecule CAS | 4345-03-03 |
| Structure method | HPLC, ESI-MS |
| Calculated properties | |
|---|---|
| LogP | 10.33265 |
| Rotatable bonds | 39 |
| H bond donor | 11 |
| H bond acceptor | 14 |
| Polar surface area (PSA) | 344.22000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
A Peptide Conjugate of Vitamin E Succinate Targets Breast Cancer Cells with High ErbB2 Expression | 2007 | Wang, Xiu-Fang; Birringer, Marc; Dong, Lan-Feng; Veprek, Pavel; Low, Pauline; Swettenham, Emma; Stantic, Marina; Yuan, Lin-Hong; Zobalova, Renata; Wu, Kun; Ledvina, Miroslav; Ralph, Stephen J.; Neuzil, Jiri | Cancer Research | ||
