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ConjuPepDB ID: cpd01125

Chemical structure


molecule
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cpd01125


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
EIYGEFKK 4-amino-α-methyl-1H-pyrazolo[3,4-d]pyrimidine-1-acetic acid
Identification
ConjuPepDB ID

cpd01125

Smiles
Molecular weight

1263.6

Molecular formula

C61H81N15O15

Chemical name
Peptide information
Sequence (one letter)

EIYGEFKK

Length

8

Peptide name

N/A

External ID
CAS number

957047-31-3

Other information
Application

Antitiumor therapy, kinase inhibition

Additional function

improved Src kinase inhibition

Pharmacological class

anticancer

Conjugate type

amide

Linker

no

Small molecule

4-amino-α-methyl-1H-pyrazolo[3,4-d]pyrimidine-1-acetic acid

Small molecule CAS

957047-66-4

Structure method

1H and 13C NMR, HPLC

NMR solvent

CDCl3

Calculated properties
LogP

-5.49881

Rotatable bonds

39

H bond donor

15

H bond acceptor

21

Polar surface area (PSA)

486.59000

Citations
ID Title Year Authors Journal DOI

cpdart0175

Synthesis and evaluation of 3-phenylpyrazolo[3,4-d]pyrimidine-peptide conjugates as Src kinase inhibitors

2007

Kumar, Anil; Wang, Yuehao; Lin, Xiaofeng; Sun, Gongqin; Parang, Keykavous

ChemMedChem

..