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View Conjugates details

ConjuPepDB ID: cpd00943

Chemical structure


molecule
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cpd00943


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
RGRKG 2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuransulfonamide
Identification
ConjuPepDB ID

cpd00943

Smiles
Inchi Key

InChIKey=VWIDQNOSRGBBHB-VYSOZWTASA-N

Molecular weight

1158.56

Molecular formula

C53H82N12O13S2

Chemical name
Peptide information
Sequence (one letter)

RGRKG

Length

5

Peptide name

Glu-AQ

External ID
CAS number

1239603-98-5

Other information
Application

Synthesis and DNA nuclease activity

Additional function

DNA cleavage, metal-free

Conjugate type

sulfonamide

Linker

no

Small molecule

2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuransulfonamide

Small molecule CAS

378230-81-0

Small molecule structure

Calculated properties
LogP

2.93301

Rotatable bonds

17

H bond donor

10

H bond acceptor

16

Polar surface area (PSA)

371.39000

Citations
ID Title Year Authors Journal DOI

Cpdart0136

A Metal-Free DNA Nuclease Based on a Cyclic Peptide Scaffold

2010

Alkhader, Shadad; Ezra, Aviva; Kasparkova, Jana; Brabec, Viktor; Yavin, Eylon

Bioconjugate Chemistry

..