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ConjuPepDB ID: cpd00830

Chemical structure


molecule
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cpd00830


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
RPKT 1,4-dihydroxyanthraquinone (quinizarin) derivative
Identification
ConjuPepDB ID

cpd00830

Smiles
Inchi Key

InChIKey=OBZDCXQUKJVRCE-DHKVTKRTSA-N

Molecular weight

793.376

Molecular formula

C38H51N9O10

Chemical name
Peptide information
Sequence (one letter)

RPKT

Length

4

Peptide name

tuftsin (liberated from the Fc domain of the heavy chain of IgG

External ID
CAS number

1283096-48-9

Other information
Application

Anticancer therapy, A549 and HL-60 cells)

Additional function

Increase activity and specific toxicity

Conjugate type

amide

Linker

no

Small molecule

1,4-dihydroxyanthraquinone (quinizarin) derivative

Small molecule CAS

81-64-1

Small molecule structure

Structure method

1H-NMR

Calculated properties
LogP

-2.17973

Rotatable bonds

19

H bond donor

10

H bond acceptor

15

Polar surface area (PSA)

321.96000

Citations
ID Title Year Authors Journal DOI

Cpdart0121

Solid phase synthesis and biological activity of tuftsin conjugates

2011

Kukowska-Kaszuba, Magdalena; Dzierzbicka, Krystyna; Serocki, Marcin; Skladanowski, Andrzej

Journal of Medicinal Chemistry

..