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View Conjugates details

ConjuPepDB ID: cpd00575

Chemical structure


molecule
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cpd00575


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
GGGPHSRN PEG ureidopyrimidinone (UPy)
Identification
ConjuPepDB ID

cpd00575

Smiles
Inchi Key

InChIKey=ISRYIVRHTDJIBP-ALSPSKABSA-N

Molecular weight

1778.96

Molecular formula

C76H130N24O25

Chemical name
Peptide information
Sequence (one letter)

GGGPHSRN

Length

8

Peptide name

N-terminal aldehyde peptide

External ID
CAS number

1358996-42-5

Other information
Application

Synthesis, self-assembly, control over the position and availability of bioactive molecules in biomaterials

Additional function

Possible application in regenerative medicine

Conjugate type

amide

Linker

N/A

Linker Type

PEG

Small molecule

ureidopyrimidinone (UPy)

Small molecule CAS

1358996-31-2

Small molecule structure

Calculated properties
LogP

-9.63237

Rotatable bonds

74

H bond donor

20

H bond acceptor

31

Polar surface area (PSA)

700.85000

Citations
ID Title Year Authors Journal DOI

Cpdart0093

Modular synthesis of supramolecular ureidopyrimidinone-peptide conjugates using an oxime ligation strategy

2012

Kieltyka, Roxanne E.; Bastings, Maartje M. C.; van Almen, Geert C.; Besenius, Pol; Kemps, Erwin W. L.; Dankers, Patricia Y. W.

Chemical Communications

..