3D model is for representation purpose only.
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KGRKKRRQRRRPPQ | 5-FAM (Hydroxyfluorescein) dye |
Identification | |
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ConjuPepDB ID | cpd00527 |
Smiles | |
Inchi Key | InChIKey=IMDXCXVSUQQHPC-OMUVQOCOSA-N |
Molecular weight | 2245.22 |
Molecular formula | C99H156N38O23 |
Chemical name | Peptide information |
Sequence (one letter) | KGRKKRRQRRRPPQ |
Length | 14 |
Peptide name | TAT-analogue |
External ID | |
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CAS number | 1427500-00-2 |
Other information | |
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Application | Anticancer therapy, KB-3-1 and KB-V1 cells |
Additional function | Improved cellular uptake and toxicity, overcome drug resistance |
Pharmacological class | anticancer |
Conjugate type | amide |
Linker | no |
Small molecule | 5-FAM (Hydroxyfluorescein) dye |
Small molecule CAS | 76823-03-05 |
Calculated properties | |
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LogP | -13.48580 |
Rotatable bonds | 70 |
H bond donor | 32 |
H bond acceptor | 41 |
Polar surface area (PSA) | 1062.62000 |
Citations | |||||
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ID | Title | Year | Authors | Journal | DOI |
Cellular uptake and cytotoxicity of drug-peptide conjugates regulated by conjugation site | 2013 | Zhang, Pengcheng; Cheetham, Andrew G.; Lock, Lye Lin; Cui, Honggang | Bioconjugate Chemistry |