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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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| XGGX | 3-(2′H-[5,6]Fullereno-C60-Ih-[1,9-c]pyrrol-1′(5′H)-yl)pentanedioic acid |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00374 |
| Smiles | |
| Inchi Key | InChIKey=UJKPRCNLUPWSSD-UHFFFAOYNA-N |
| Molecular weight | 1163.35 |
| Molecular formula | C87H45N3O2 |
| Chemical name | Peptide information |
| Sequence (one letter) | XGGX |
| Length | 4 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 1577256-63-3 |
| Other information | |
|---|---|
| Application | Synthesis |
| Additional function | Fulleropeptide conjugates with improved cell penetration property, higher water solubility and possible antimicrobial activity |
| Pharmacological class | other |
| Conjugate type | amine |
| Linker | no |
| Small molecule | 3-(2′H-[5,6]Fullereno-C60-Ih-[1,9-c]pyrrol-1′(5′H)-yl)pentanedioic acid |
| Small molecule CAS | 1577256-59-7 |
| Small molecule structure | |
| Calculated properties | |
|---|---|
| LogP | 14.36902 |
| Rotatable bonds | 19 |
| H bond donor | 2 |
| H bond acceptor | 3 |
| Polar surface area (PSA) | 61.44000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
C60 Pyrrolidine Bis-carboxylic Acid Derivative as a Versatile Precursor for Biocompatible Fullerenes | 2014 | Aroua, Safwan; Schweizer, W. Bernd; Yamakoshi, Yoko | Organic Letters | ||
