conjupepdb_log

View Conjugates details

ConjuPepDB ID: cpd00371

Chemical structure


molecule
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cpd00371


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
GGGPKKKRKVGA butane telithromycin (TEL) derivative
Identification
ConjuPepDB ID

cpd00371

Smiles
Inchi Key

InChIKey=AGDNMBDQCWVHAW-YPKUIQDGSA-N

Molecular weight

1900.16

Molecular formula

C87H153N25O22

Chemical name
Peptide information
Sequence (one letter)

GGGPKKKRKVGA

Length

12

Peptide name

designed oligopeptides

External ID
CAS number

1629893-85-1

Other information
Application

Synthesis

Additional function

Probes for interrogating nascent peptide-exit tunnel interaction from the PTC to the exit tunnel entrance

Pharmacological class

other

Conjugate type

triazole

Linker

N/A

Linker Type

butane

Small molecule

telithromycin (TEL) derivative

Small molecule CAS

849407-75-6

Small molecule structure

Calculated properties
LogP

-7.32228

Rotatable bonds

54

H bond donor

19

H bond acceptor

31

Polar surface area (PSA)

720.75000

Citations
ID Title Year Authors Journal DOI

Cpdart0070

Macrolide-Peptide Conjugates as Probes of the Path of Travel of the Nascent Peptides through the Ribosome

2014

Washington, Arren Z.; Benicewicz, Derek B.; Canzoneri, Joshua C.; Fagan, Crystal E.; Mwakwari, Sandra C.; Maehigashi, Tatsuya; Dunham, Christine M.; Oyelere, Adegboyega K.

ACS Chemical Biology

..