conjupepdb_log

View Conjugates details

ConjuPepDB ID: cpd00353

Chemical structure


molecule
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cpd00353


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
IEPXYRLRY triazole R,S-propargyloxyproline
Identification
ConjuPepDB ID

cpd00353

Smiles
Inchi Key

InChIKey=XJBSQJNCYWPMIB-XLTFOLQXSA-N

Molecular weight

1351.68

Molecular formula

C65H90FN17O14

Chemical name
Peptide information
Sequence (one letter)

IEPXYRLRY

Length

9

Peptide name

nonapeptide

External ID
CAS number

1809332-09-9

Other information
Application

Synthesis, Y1-receptor binding

Additional function

Preparation of biotin and fluorophore-labelled peptides

Pharmacological class

other

Conjugate type

ether

Linker

N/A

Linker Type

triazole

Small molecule

R,S-propargyloxyproline

Small molecule CAS

1267640-69-6

Small molecule structure

Calculated properties
LogP

-2.93324

Rotatable bonds

33

H bond donor

16

H bond acceptor

20

Polar surface area (PSA)

503.79000

Citations
ID Title Year Authors Journal DOI

Cpdart0066

Propargyloxyproline regio- and stereoisomers for Click-conjugation of peptides: Synthesis and application in linear and cyclic peptides

2015

Northfield, Susan E.; Mountford, Simon J.; Wielens, Jerome; Liu, Mengjie; Zhang, Lei; Herzog, Herbert; Holliday, Nicholas D.; Scanlon, Martin J.; Parker, Michael W.; Chalmers, David K.; Thompson, Philip E.

Australian Journal of Chemistry

..