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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| GGGGXGDS | 9-Fluorenylmethyl chloroformate |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00294 |
| Smiles | |
| Inchi Key | InChIKey=NMMNFZIWNBYLTQ-SVWSIEHRSA-N |
| Molecular weight | 1247.55 |
| Molecular formula | C59H81N11O17S |
| Chemical name | Peptide information |
| Sequence (one letter) | GGGGXGDS |
| Length | 8 |
| Peptide name | octapeptide |
| External ID | |
|---|---|
| CAS number | 1826066-61-8 |
| Other information | |
|---|---|
| Application | Synthesis, supramolecular UPy–peptide conjugate polymer |
| Additional function | Possible biomaterial applications |
| Pharmacological class | other |
| Conjugate type | sulfonamide |
| Linker | no |
| Small molecule | 9-Fluorenylmethyl chloroformate |
| Small molecule CAS | 28920-43-6 |
| Small molecule structure | |
| Small molecule 2 | 2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuransulfonamide |
| Small molecule CAS 2 | 378230-81-0 |
| Small molecule structure 2 | |
| Calculated properties | |
|---|---|
| LogP | -1.30222 |
| Rotatable bonds | 31 |
| H bond donor | 11 |
| H bond acceptor | 17 |
| Polar surface area (PSA) | 408.64000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Solid-phase-based synthesis of ureidopyrimidinone-peptide conjugates for supramolecular biomaterials | 2015 | de Feijter, Isja; Goor, Olga J. G. M.; Hendrikse, Simone I. S.; Comellas-Aragones, Marta; Soentjens, Serge H. M.; Zaccaria, Sabrina; Fransen, Peter P. K. H.; Peeters, Joris W.; Milroy, Lech-Gustav; Dankers, Patricia Y. W. | Synlett | ||
