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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| GGRGDS | PEG | ureidopyrimidinone |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00276 |
| Smiles | |
| Inchi Key | InChIKey=BQFTZEUEXCPGDD-IGMOWHQGSA-N |
| Molecular weight | 1315.67 |
| Molecular formula | C54H93N17O21 |
| Chemical name | Peptide information |
| Sequence (one letter) | GGRGDS |
| Length | 6 |
| Peptide name | hexapeptide |
| External ID | |
|---|---|
| CAS number | 1826067-02-0 |
| Other information | |
|---|---|
| Application | Synthesis, supramolecular UPy–peptide conjugate polymer |
| Additional function | Possible biomaterial applications |
| Pharmacological class | other |
| Conjugate type | amide |
| Linker | N/A |
| Linker Type | PEG |
| Small molecule | ureidopyrimidinone |
| Small molecule CAS | 320393-85-19 |
| Calculated properties | |
|---|---|
| LogP | -11.28295 |
| Rotatable bonds | 54 |
| H bond donor | 18 |
| H bond acceptor | 26 |
| Polar surface area (PSA) | 561.90000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Solid-phase-based synthesis of ureidopyrimidinone-peptide conjugates for supramolecular biomaterials | 2015 | de Feijter, Isja; Goor, Olga J. G. M.; Hendrikse, Simone I. S.; Comellas-Aragones, Marta; Soentjens, Serge H. M.; Zaccaria, Sabrina; Fransen, Peter P. K. H.; Peeters, Joris W.; Milroy, Lech-Gustav; Dankers, Patricia Y. W. | Synlett | ||
