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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| GQSYD | Dansylglycine |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd00227 |
| Smiles | |
| Inchi Key | InChIKey=ZAONUTBDUCUXPH-DLWBLUATSA-N |
| Molecular weight | 1211.56 |
| Molecular formula | C66H81N7O13S |
| Chemical name | Peptide information |
| Sequence (one letter) | GQSYD |
| Length | 5 |
| Peptide name | pentapeptide |
| External ID | |
|---|---|
| CAS number | 1839533-25-3 |
| Other information | |
|---|---|
| Application | Synthesis, peptide-peptide ineraction inhibition |
| Additional function | Possible applications in cancers and neurolodegenerative diseases |
| Pharmacological class | other |
| Conjugate type | sulfonamide |
| Linker | no |
| Small molecule | Dansylglycine |
| Small molecule CAS | 1091-85-6 |
| Small molecule structure | |
| Calculated properties | |
|---|---|
| LogP | 6.01140 |
| Rotatable bonds | 30 |
| H bond donor | 7 |
| H bond acceptor | 13 |
| Polar surface area (PSA) | 276.97000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Intracellular Generation of a Diterpene-Peptide Conjugate that Inhibits 14-3-3-Mediated Interactions | 2015 | Parvatkar, Prakash; Kato, Nobuo; Uesugi, Motonari; Sato, Shin-ichi; Ohkanda, Junko | Journal of the American Chemical Society | ||
