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View Conjugates details

ConjuPepDB ID: cpd00103

Chemical structure


molecule
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cpd00103


Schematic Help Icon Schematic representation of peptide, linker and drug in the peptide-drug conjugates
GWGVP butyric acid 3,4-Dihydro-4-oxo-2-quinazolinebutanoic acid
Identification
ConjuPepDB ID

cpd00103

Smiles
Inchi Key

InChIKey=NRXOOVPPYFFFMT-BVCQTOFBSA-N

Molecular weight

818.375

Molecular formula

C44H50N8O8

Chemical name
Peptide information
Sequence (one letter)

GWGVP

Length

5

Peptide name

N/A

External ID
CAS number

2411424-06-9

Other information
Application

Antimicrobial therapy, antibacteraial (Gramm-positive and negative)

Additional function

Improve effect

Pharmacological class

antimicrobial, antibacterial

Conjugate type

amide

Linker

N/A

Linker Type

butyric acid

Small molecule

3,4-Dihydro-4-oxo-2-quinazolinebutanoic acid

Small molecule CAS

95494-51-2

Small molecule structure

Structure method

1H- and 13C-NMR

Calculated properties
LogP

2.52598

Rotatable bonds

19

H bond donor

6

H bond acceptor

9

Polar surface area (PSA)

220.26000

Citations
ID Title Year Authors Journal DOI

Cpdart0032

Effect of low charge and high hydrophobicity on antimicrobial activity of the quinazolinone-peptide conjugates

2018

Rakesh, Kadallipura Puttaswamy; Ramesh, Suhas; Shivakumar; Gowda, Dase Channe

Russian Journal of Bioorganic Chemistry

..