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Schematic representation of peptide, linker and drug in the peptide-drug conjugates
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|---|---|---|---|---|
| XGFLG | Methotrexate |
| Identification | |
|---|---|
| ConjuPepDB ID | cpd01285 |
| Smiles | |
| Molecular weight | 930.392 |
| Molecular formula | C42H54N14O9S |
| Chemical name | Peptide information |
| Sequence (one letter) | XGFLG |
| Length | 5 |
| Peptide name | N/A |
| External ID | |
|---|---|
| CAS number | 900179-58-0 |
| Other information | |
|---|---|
| Application | Anticancer therapy |
| Additional function | Targeting, chemotactic |
| Pharmacological class | anticancer |
| Conjugate type | amide |
| Linker | no |
| Small molecule | Methotrexate |
| Small molecule CAS | 59-05-2 |
| Structure method | RP-HPLC |
| Calculated properties | |
|---|---|
| LogP | -1.83948 |
| Rotatable bonds | 24 |
| H bond donor | 11 |
| H bond acceptor | 16 |
| Polar surface area (PSA) | 361.83000 |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Synthesis of oligotuftsin-based branched oligopeptide conjugates for chemotactic drug targeting | 2006 | Mezo, Gabor; Lang, Orsolya; Jakab, Annamaria; Bai, Katalin B.; Szabo, Ildiko; Schlosser, Gitta; Lang, Julianna; Kohidai, Laszlo; Hudecz, Ferenc | Journal of Peptide Science | ||
